What Happens When You Support Phase II Detoxification by Making Glutathione Again?
- debbierolls1979
- Nov 19
- 3 min read

Our glutathione production naturally drops with age
From about our mid-20s onward, our glutathione levels begin to decline steadily. By the time we hit our 40s, 50s, and beyond, studies show our levels can drop 30–50%. Lower glutathione levels lead to greater oxidative stress, slower detoxification, and increased inflammation.
When people talk about “detoxing,” they often picture juice cleanses, fasting, or cutting out sugar. But your body has a built-in detox system that’s far more powerful and far more important — your liver. And inside your liver, there’s a two-step process that determines how well you can neutralise toxins, hormones, chemicals, inflammation by-products, and everyday metabolic waste.
Phase I breaks things apart. Phase II packages them for safe removal from the body.
And the superhero of Phase II detoxification is glutathione.
Why Glutathione Matters So Much
Glutathione is often called the body’s “master antioxidant.”But it’s more than that — it acts like a chemical binder, a neutraliser, a protector, a cleaner, and a traffic controller all at once.
When you have healthy glutathione levels, your liver can:
Neutralise toxins so they don’t cause damage
Attach toxins to glutathione molecules so they can be excreted
Reduce inflammation triggered by oxidative stress
Help recycle other antioxidants like vitamin C
Protect your mitochondria (your cellular energy engines)
But here’s the catch: Stress, inflammation, poor sleep, processed foods, alcohol, medications, and simply aging all lower glutathione production.
So when glutathione runs low, Phase II detox slows down, and toxins that should leave your body start circling back into your system — leading to fatigue, brain fog, sluggishness, skin issues, chemical sensitivity, and more.
What Happens When You Support Glutathione Production Again
When you support Phase II detox and help your body make glutathione again, the change is like finally giving your liver the team of workers it has been begging for.
Here’s what usually improves:
1. Toxins stop recirculating
Without glutathione, toxins get “stuck” mid-detox. With glutathione, your liver can finally bind them and eliminate them through bile or the kidneys.
2. Inflammation naturally lowers
Glutathione helps calm oxidative stress — the fire behind premature aging, chronic inflammation, and sluggish energy.
When inflammation lowers, people often notice:
clearer skin
less bloating
fewer aches
better focus
calmer moods
3. Hormone balance becomes easier
Phase II is responsible for clearing out “used” hormones — especially estrogen. Supporting this pathway helps prevent hormonal buildup that can lead to PMS, mood swings, skin breakouts, and fluid retention.
4. Your energy system turns back on
Glutathione protects mitochondria and helps them produce cleaner, more efficient energy.
You often feel:
lighter
less foggy
more resilient
more stable throughout the day
5. Your body becomes more resilient to daily stress
A supported liver = a supported nervous system.
People often describe it as:
“I just cope better.”
Why Phase II Support Matters More Than Ever
Your Phase II detox system wasn’t built for modern life. It wasn’t designed to handle hundreds of chemicals, processed foods, plastics, pesticides, and stress hormones 24/7.
Supporting glutathione is like giving your liver the green light to catch up — and then thrive.
When your body can detoxify properly, it doesn’t have to “hold” onto inflammation, toxins, or hormonal waste. You function the way you were designed to.
The Bottom Line
Supporting Phase II detoxification by helping your body make glutathione again isn’t just about “detoxing.”It’s about:
protecting your cells
lowering inflammation
improving energy
supporting hormones
enhancing resilience
restoring balance
Your liver is doing its job for you every minute of every day. When you support it with glutathione, it finally has the power to work with you, not against you.
Love & Light xox




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